New Database Available - Released on 29/09/2026.
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1
Unique InChIKey
47
Unique Receptor Sequence
4
Unique Co-Receptor Sequence
1
EC50 Parameter
7
Unique DOI
Results
Showing 31 to 58 of 58 results
 
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Species
Name
Mutated
Species
Name
Mutated
Responsive
Parameter
Value Nature
Nb. Measurements
–
Experimental Technique
Recording System
Type
Expression System
Expression Cell Type
Expression Driver
Odor Delivery System
Reference
Receptor Co-Receptor Molecule Response Bioassay Resources
Species
Name
Accession
Mutation
Sequence
Species
Name
Accession
Mutation
Sequence
Name
CAS
InChIKey
CID
SMILES
Mixture
Responsive
Parameter
Value
Value Nature
Concentration
Nb. measurements
Experimental Technique
Recording System
Type
Expression System
Expression Cell Type
Expression Driver
Odor Delivery System
Stimulation Flux
Main Flux
Stimulation Duration
Reference
DOI
Reference Position
Drosophila melanogaster Or22a P81909 - MLSKFFPHIKEKPLSERVKSRDAFIYLDRV ... Drosophila melanogaster Orco Q9VNB5 - MTTSMQPSKYTGLVADLMPNIRAMKYSGLF ... alpha-Pinene, (+)-
(+)-α-pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Dose-Response N.A. EC50 N.A. 11 Calcium Imaging Olympus BX50WI ∆ Fluorescence Drosophila wild-type OSN endogenous promoter Head Space 1 mL/s 1 mL/s 2 s Pelz, D., Roeske, T., Syed, Z. ... 10.1002/neu.20333 Table 2
Ips typographus Or36 WZI48883.1 - MASDEFIKIPKIFLILGGFWPFSVTKDPLK ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.366 %Δ fluorescence Norm. other 30 µM 9 HEK293 Omega FluoStar Calcium Imaging Human HEK293 AGAATGCGGCCGCCACCATGGGCAAGCCTATCCCTAATCCTCTGCTGGGCCTGGACAGCACCGCGAGTGACGAGTTTATA Liquid N.A. N.A. N.A. Yuvaraj, J. K., Kandasamy, D., ... 10.1186/s12915-024-02066-x Additional File 2
Ips typographus Or23 A0A8F3ERX1 - MAVYPKSEHLKVPAIYCSTIGIFPWKFMFQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary N.A. Norm. other 100 µM 4 Two-electrode Voltage Clamp TEC-03BF Current Amplitude Xenopus oocytes N.A. N.A. Liquid 2 mL/min N.A. 20 s Hou, X.-Q., Yuvaraj, J. K., Ro ... 10.1093/molbev/msab218 Table 1
Ips typographus Or25 A0A8F3ERC7 - MKIYPDTKFFDVTAKFGAIVGLYPWQFMFP ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular Yes Dose-Response N.A. Norm. other 100 µM 4 Two-electrode Voltage Clamp TEC-03BF Current Amplitude Xenopus oocytes N.A. N.A. Liquid 2 mL/min N.A. 20 s Hou, X.-Q., Yuvaraj, J. K., Ro ... 10.1093/molbev/msab218 Table 1
Ips typographus Or27 A0A8F3EVI2 - MRVYPDIENFKITAIYSSTIGLFPWKFMFQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary N.A. Norm. other 100 µM 4 Two-electrode Voltage Clamp TEC-03BF Current Amplitude Xenopus oocytes N.A. N.A. Liquid 2 mL/min N.A. 20 s Hou, X.-Q., Yuvaraj, J. K., Ro ... 10.1093/molbev/msab218 Table 1
Ips typographus Or29 A0A8F3IVT0 K111E MAAYPQCKNLRVAIIYSSIIGVFPWQFMFQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary N.A. Norm. other 100 µM 4 Two-electrode Voltage Clamp TEC-03BF Current Amplitude Xenopus oocytes N.A. N.A. Liquid 2 mL/min N.A. 20 s Hou, X.-Q., Yuvaraj, J. K., Ro ... 10.1093/molbev/msab218 Table 1
Ips typographus Or28 A0A8F3IXZ3 - MGLYPASRYFKNPIMWSSILGAFPWQMIFQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary N.A. Norm. other 100 µM 4 Two-electrode Voltage Clamp TEC-03BF Current Amplitude Xenopus oocytes N.A. N.A. Liquid 2 mL/min N.A. 20 s Hou, X.-Q., Yuvaraj, J. K., Ro ... 10.1093/molbev/msab218 Figure 6
Ips typographus Or23 A0A8F3ERX1 - MGKPIPNPLLGLDSTAVYPKSEHLKVPAIY ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -0.188 % Norm. receptor 3.000e-5 M 4 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Datasheet 1
Ips typographus Or23 A0A8F3ERX1 - MGKPIPNPLLGLDSTAVYPKSEHLKVPAIY ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.491 % Norm. receptor 3.000e-5 M 4 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Datasheet 1
Ips typographus Or25 A0A8F3ERC7 - MGKPIPNPLLGLDSTKIYPDTKFFDVTAKF ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.857 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Figure 3 ; Datasheet 1
Ips typographus Or25 A0A8F3ERC7 - MGKPIPNPLLGLDSTKIYPDTKFFDVTAKF ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -0.896 % Norm. receptor 3.000e-5 M 4 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Figure 3 ; Datasheet 1
Ips typographus Or27 A0A8F3EVI2 - MGKPIPNPLLGLDSTRVYPDIENFKITAIY ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 1.984 % Norm. receptor 3.000e-5 M 4 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Datasheet 1
Ips typographus Or27 A0A8F3EVI2 - MGKPIPNPLLGLDSTRVYPDIENFKITAIY ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -1.794 % Norm. receptor 3.000e-5 M 4 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Datasheet 1
Ips typographus Or28 A0A8F3IXZ3 - MGKPIPNPLLGLDSTGLYPASRYFKNPIMW ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -6.794 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Datasheet 1
Ips typographus Or28 A0A8F3IXZ3 - MGKPIPNPLLGLDSTGLYPASRYFKNPIMW ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -0.489 % Norm. receptor 3.000e-5 M 4 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Datasheet 1
Ips typographus Or29 A0A8F3IVT0 K111E MGKPIPNPLLGLDSTAAYPQCKNLRVAIIY ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -0.23 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Figure 5 ; Datasheet 1
Ips typographus Or29 A0A8F3IVT0 K111E MGKPIPNPLLGLDSTAAYPQCKNLRVAIIY ... Ips typographus Orco A0A7L8XYY7 M1L MEQKLISEEDLMNKFKVAGLVADLMPNIRL ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -2.037 % Norm. receptor 3.000e-5 M 2 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Yuvaraj, J. K. ... 10.3389/fncel.2021.744401 Figure 5 ; Datasheet 1
Dendroctonus ponderosae Or8 XP_048521609.1 - MGKPIPNPLLGLDSTIKQPSYEVYATDFFS ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.681 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Biswas, T., Yu ... 10.1111/mec.16494 Data S1
Dendroctonus ponderosae Or9 XP_019768310.1 - MGKPIPNPLLGLDSTDTLGPALTKVRLRLP ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.079 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Biswas, T., Yu ... 10.1111/mec.16494 Data S1
Hylobius abietis Or3 UQK85193 - MFNRTYARDFFVVNRWMLMCAGLWRPETKN ... Hylobius abietis Orco Not available - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -0.5 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Biswas, T., Yu ... 10.1111/mec.16494 Data S1
Hylobius abietis Or4 UQK85194.1 I12T MGKPIPNPLLGLDSTTFITGADNLQTESKN ... Hylobius abietis Orco Not available - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary -0.301 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Biswas, T., Yu ... 10.1111/mec.16494 Data S1
Ips typographus Or5 XP_081828105 - MLNHDYPKNVLSSVDTILLICGLGKISKKI ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.495 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Biswas, T., Yu ... 10.1111/mec.16494 Data S1
Ips typographus Or6 XP_081832923 - MLRKNPRYATDFFSVNQWMLRRAGLWRPSN ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary 0.834 % Norm. receptor 3.000e-5 M 6 Calcium Imaging CLARIOstar Omega plate reader (BMG Labtech) ∆ Fluorescence Hek HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Roberts, R. E., Biswas, T., Yu ... 10.1111/mec.16494 Data S1
Ips typographus Or46 A0A7L8XZ66 - MNAFPDSDSLTALKFTSVLGLFPWKLAFQQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary < 3 % Norm. receptor 30 µM 9 Calcium Imaging FLUOstar Omega plate reader ∆ Fluorescence Hek TREx/HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Yuvaraj, J. K., Roberts, R. E. ... 10.1186/s12915-020-00946-6 Supplementary Data 2
Ips typographus Or49 A0A7L8XYT4 - MTMTIYPKTENMRLTAIYSSTLGIFPWKFL ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary < 3 % Norm. receptor 30 µM 9 Calcium Imaging FLUOstar Omega plate reader ∆ Fluorescence Hek TREx/HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Yuvaraj, J. K., Roberts, R. E. ... 10.1186/s12915-020-00946-6 Supplementary Data 2
Ips typographus Or46 A0A7L8XZ66 Y84F MNAFPDSDSLTALKFTSVLGLFPWKLAFQQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary < 3 % Norm. receptor 30 µM 9 Calcium Imaging FLUOstar Omega plate reader ∆ Fluorescence Hek TREx/HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Yuvaraj, J. K., Roberts, R. E. ... 10.1186/s12915-020-00946-6 Supplementary Data 2
Ips typographus Or46 A0A7L8XZ66 Y84A MNAFPDSDSLTALKFTSVLGLFPWKLAFQQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary < 3 % Norm. receptor 30 µM 9 Calcium Imaging FLUOstar Omega plate reader ∆ Fluorescence Hek TREx/HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Yuvaraj, J. K., Roberts, R. E. ... 10.1186/s12915-020-00946-6 Supplementary Data 2
Ips typographus Or46 A0A7L8XZ66 T205A MNAFPDSDSLTALKFTSVLGLFPWKLAFQQ ... Ips typographus Orco A0A7L8XYY7 - MMNKFKVAGLVADLMPNIRLIQASGHFMFN ... alpha-Pinene, (+)-
(+)-α-Pinene 		7785-70-8 GRWFGVWFFZKLTI-RKDXNWHRSA-N 82227 CC1=CC[C@@H]2C[C@H]1C2(C)C Monomolecular No Primary < 3 % Norm. receptor 30 µM 9 Calcium Imaging FLUOstar Omega plate reader ∆ Fluorescence Hek TREx/HEK293 pcDNA5/TO Liquid N.A. N.A. N.A. Yuvaraj, J. K., Roberts, R. E. ... 10.1186/s12915-020-00946-6 Supplementary Data 2
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